Focuses on enterprise-level information systems, technologies, and infrastructures that are emerging as the first generation 21st century application integration design strategies and tools. Included are managing web-based client/server and distributed environments, evaluation of vendor strategies, legacy system migration issues, performance, interoperability, scalability, and security concerns, web services foundations, types of middleware, vendor architectures, distributed applications, the context for integration, service-oriented application integration, multi-enterprise portals, mobile devices, business process integration, Java-based middleware standards, web services APIs, and emerging standards. Cases of enterprise systems and architectures are analyzed.